Cleviprex Impurity 11 - Names and Identifiers
Name | 4-(2,3-Dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylic acid
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Synonyms | Felodipine Diacid Dicarboxy Felodipine Cleviprex Impurity 11 Felodipine Impurity 6 Clevidipine Impurity 9 Clevidipine Butyrate Impurity K 4-(2,3-Dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 4-(2,3-DICHLORO-PHENYL)-2,6-DIMETHYL-1,4-DIHYDRO-PYRIDINE-3,5-DICARBOXYLIC ACID 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-diMethyl-
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CAS | 138279-32-0
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Cleviprex Impurity 11 - Physico-chemical Properties
Cleviprex Impurity 11 - Upstream Downstream Industry
Cleviprex Impurity 11 - Introduction
4-(2,3-dichlorophenyl) -2,6-diethyl-1, 4-dihydropyridine-3,5-dicarboxylic acid(4-(2,3-dichlorophenyl) -2,6-diethyl-1, 4-dihydropyridine-3,5-dicarboxylic acid is an organic compound), its chemical structure contains chlorine and methyl groups. The following is an introduction to its nature, use, preparation and safety information:
Properties: 4-(2,3-dichlorophenyl) -2,6-dimethy1-1, 4-dihydropyridine-3,5-dicarboxylic acid is a white solid, its chemical name is 4-(2,3-dichlorophenyl)-2,6-dimethyl -1,4-dihydropyridine-3,5-dicarboxylic acid. It is stable at room temperature and pressure, and its relative solubility in solvents is moderate.
use: 4-(2,3-dichlorophenyl)-2,6-dimethyl-1, 4-dihydropyridine-3,5-dicarboxylic acid is mainly used as an intermediate of drugs in the synthesis of clevidipine (an antihypertensive drug) generated in the process. It plays the role of connecting different parts in the process of drug synthesis and is one of the key intermediates of drugs.
preparation method: the preparation method of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1, 4-dihydropyridine-3,5-dicarboxylic acid is to carry out condensation reaction between p-dichloroacetophenone and pyridine, 4-(2,3-dichlorophenyl) -2,6-dimethyl-1, 4-dihydropyridine-3,5-dicarboxylic acid is generated by the reduction of Formic Anhydride and thionyl chloride. This reaction process requires a multi-step reaction, and the use of organic synthesis technology for control and separation and purification.
SAFETY INFORMATION: There is currently limited information on the toxicity and safety of 4-(2,3-dichlorophenyl) -2,6-dimethyl-1, 4-dihydropyridine-3,5-dicarboxylic acid. Because it is an intermediate of drugs, a series of purification and detection steps are usually carried out in the process of drug synthesis to ensure that the prepared drugs meet the quality standards and safety requirements. However, when operating in the laboratory, necessary protective measures should be taken to avoid direct contact with the skin and inhalation of its dust or steam to prevent potential hazards. If you want to contact or exposure, please seek professional guidance and treatment in a timely manner.
Last Update:2024-04-09 18:58:34